In an interview with The Daily Mail Scherzinger explained that she had been brought up with a strict religious (Catholic) upbringing in Hawaii. She first attended Meyzeek Middle School as an adolescent. Growing up, Nicole states that she didn't have a lot of money and the singer thanks her mom for all the support she gave her to become what she is today. Scherzinger began performing in Louisville, attending the Youth Performing Arts School at duPont Manual High School and performing with Actors Theatre of Louisville.
As a teenager, Scherzinger was the first runner-up at the 1996 Kentucky State Fair's Coca-Cola Talent Classic contest. she also was the Queen for the Louisville Barrio Fiesta, a celebration of all Filpinos in the area. Scherzinger majored in acting and musical theatre at Wright State University, where she played Velma Kelly in Chicago and Julie La Verne in Show Boat, but put her studies on hold in 1999 to sing backing vocals for the rock band Days of the New.